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DUSP22 Polyclonal Antibody

CAT: 0763-E-AB-14065-04Size: 200 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-14065-04Size:200 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. DUSP22 dephosphorylates ERK2 MAP kinase and JNK. DUSP22 displays highest in thymus, but it is also detectable in monocytes and lymphocytes.
Abbreviation
DUSP22
UniProt
Q9NRW4
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Recombinant protein of human DUSP22
Target
Dual specificity protein phosphatase 22; DUS22; Dusp22; JNK stimulatory phosphatase 1; JNK-stimulatory phosphatase-1; JSP 1; JSP-1; JSP1; LMW DSP2; LMW-DSP2; Low molecular weight dual specificity phosphatase 2; MAP kinase phosphatase x; Mitogen activated protein kinase phosphatase x; Mitogen-activated protein kinase phosphatase x; MKP-x; MKPX
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cell Biology; Signal Transduction
Purification
Affinity purification
Concentration
0.4 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · Q9NRW4

Dual specificity protein phosphatase 22

DUS22_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9NRW4
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
DUSP22
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.1.3.16, 3.1.3.48
Processing
—
Secondary accessions
B4DK56, Q59GW2, Q5VWR2, Q96AR1
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cytoplasm

Molecular function

HydrolaseProtein phosphatase

Biological process

Immunity

PTM

LipoproteinMyristatePhosphoprotein

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