DUSP12 Polyclonal Antibody

• Background:

  The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain.

• Abbreviation:

  DUSP12

• UniProt:

  Q9UNI6

• Host:

  Rabbit

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Recombinant protein of human DUSP12

• Target:

  Dual specificity phosphatase 12; Dual specificity protein phosphatase 12; Dual specificity tyrosine phosphatase YVH1; DUS12; DUSP 1; DUSP 12; DUSP1; DUSP12; Serine/threonine specific protein phosphatase; TDSP4; YVH 1; YVH1; YVH1 protein tyrosine phosphatase (S. cerevisiae) ortholog; YVH1 protein tyrosine phosphatase ortholog

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB

• Field of Research:

  Signal Transduction

• Purification:

  Affinity purification

• Concentration:

  0.4 mg/mL

• Dilution:

  WB 1:200-1:1000

• Buffer:

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  38kDa

• Isotype:

  IgG