CCL4 Polyclonal Antibody

• Background :

  The protein encoded by this gene is a mitogen-inducible monokine and is one of the major HIV-suppressive factors produced by CD8+ T-cells. The encoded protein is secreted and has chemokinetic and inflammatory functions. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV) . The processed form MIP-1-beta (3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta (3-69) is also a ligand for CCR1 and CCR2 isoform B.

• Abbreviation :

  CCL4

• UniProt :

  P13236

• Host :

  Rabbit

• Reactivity :

  Human; Rat

• Immunogen :

  Recombinant protein of human CCL4

• Target :

  ACT2; G-26; HC21; LAG1; LAG-1; MIP1B; SCYA2; SCYA4; MIP1B1; AT744.1; MIP-1-beta

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Applications :

  IHC

• Field of Research :

  Immunology

• Purification :

  Affinity purification

• Concentration :

  0.6 mg/mL

• Dilution :

  IHC 1:50-1:200

• Buffer :

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Shipping Conditions :

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Isotype :

  IgG