CCL2 Polyclonal Antibody

CAT: 0763-E-AB-40274-01Size: 25 µLDry Ice: NoHazardous: No
CAT#:0763-E-AB-40274-01Size:25 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.
Abbreviation
CCL2
UniProt
P13500
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human C-C motif chemokine 2 protein
Target
C-C motif chemokine 2; CCL2; CCL2; Chemokine (C C motif) ligand 2; GDCF 2; GDCF-2; GDCF2; HC11; HSMCR30; JE; MCAF; MCP 1; MCP-1; MCP1; MGC9434; Monocyte chemoattractant protein 1; Monocyte chemotactic and activating factor; Monocyte chemotactic protein 1; Monocyte secretory protein JE; SCYA2; Small inducible cytokine A2 (monocyte chemotactic protein 1; homologous to mouse Sig je) ; Small inducible cytokine A2; Small inducible cytokine subfamily A (Cys Cys) ; member 2; Small-inducible cytokine A2; SMC CF; SMC-CF; SMCCF
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Cardiovascular; Metabolism; Immunology
Purification
Antigen Affinity Purification
Concentration
1 mg/mL
Dilution
IHC 1:100-1:200
Buffer
PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

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