SLIT2 Polyclonal Antibody

• Background :

  Secreted leucine-rich repeat-containing proteins 1-3 (Slit1-3) are secreted glycoproteins that influence axonal guidance and mediate normal neural development by acting as high-affinity signaling ligands for the repulsive guidance receptor, Roundabout (Robo. Within the developing central nervous system (CNS) of different vertebrate systems, Slit proteins are expressed in equivalent regions, suggesting a conserved function among vertebrate homologs. Slit is expressed in the midline of the central nervous system in both vertebrates and invertebrates, where it functions as a regulatory factor of mesodermal cell movement during gastrulation. Slit2 is a short range inhibitory guidance cue for retinal ganglion cell (RGC) axons that may mediate spatial progression of RGCs.

• Abbreviation :

  SLIT2

• UniProt :

  O94813

• Host :

  Rabbit

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  Synthetic peptide of human SLIT2

• Target :

  Drad 1; E030015M03Rik; E130320P19Rik; FLJ14420; OTTHUMP00000158695; OTTHUMP00000217852; OTTHUMP00000217853; OTTHUMP00000217854; Slil 3; Slil3; Slit 2; Slit homolog 2 (Drosophila) ; Slit homolog 2; Slit homolog 2 protein; Slit homolog 2 protein C-product; Slit-2; Slit2; SLIT2

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Applications :

  WB; IHC

• Field of Research :

  Cancer; Neuroscience

• Purification :

  Affinity purification

• Concentration :

  0.3 mg/mL

• Dilution :

  WB 1:500-1:2000; IHC 1:25-1:100

• Buffer :

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Shipping Conditions :

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  170kDa

• Isotype :

  IgG