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SLC8A3 Polyclonal Antibody

CAT: 0763-E-AB-13657-02Size: 60 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-13657-02Size:60 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the sodium/calcium exchanger integral membrane protein family. Na+/Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes, where exchange of Na+ for Ca2+ occurs in an electrogenic manner. Alternative splicing has been observed for this gene and multiple variants have been described.
Abbreviation
SLC8A3
UniProt
P57103
Host
Rabbit
Reactivity
Human; Rat
Immunogen
Synthetic peptide of human SLC8A3
Target
AW742262; MGC90626; Na+/Ca2+ exchange protein 3; Na+/Ca2+ exchanger 3; NAC3; NCX3; SCL8A3; Sodium calcium exchanger form 3; Sodium/calcium exchanger 3; Sodium/calcium exchanger SLC8A3; Solute carrier family 8 sodium calcium exchanger member 3
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Metabolism; Signal Transduction
Purification
Affinity purification
Concentration
0.8 mg/mL
Dilution
IHC 1:25-1:100
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · P57103

Sodium/calcium exchanger 3

NAC3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P57103
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SLC8A3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
Q5K3P6, Q5K3P7, Q8IUE9, Q8IUF0, Q8NFI7, Q96QG1, Q96QG2
Protein keywords

Coding sequence diversity

Alternative splicing

Biological process

AntiportCalcium transportIon transportSodium transportTransport

Ligand

CalciumMetal-bindingSodium

Molecular function

Calmodulin-binding

Cellular component

Cell junctionCell membraneCell projectionCytoplasmEndoplasmic reticulumMembraneMitochondrionMitochondrion outer membraneSynapse

PTM

Glycoprotein

Technical term

Proteomics identificationReference proteome

Domain

RepeatSignalTransmembraneTransmembrane helix

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