SYN2 Polyclonal Antibody

CAT: 0763-E-AB-13331-02Size: 60 µLDry Ice: NoHazardous: No

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CAT#:0763-E-AB-13331-02Size:60 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family encodes a neuron-specific phosphoprotein that selectively binds to small synaptic vesicles in the presynaptic nerve terminal. The TIMP4 gene is located within an intron of this gene and is transcribed in the opposite direction. Mutations in this gene may be associated with abnormal presynaptic function and schizophrenia. Alternative splicing of this gene results in two transcripts.

Abbreviation

SYN2

UniProt

Q92777

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Synthetic peptide of human SYN2

Target

SYN 2; SYN II; SYN IIa; SYN IIb; SYN2; Synapsin 2; Synapsin II isoform IIa; Synapsin II isoform IIb; Synapsin2; SynapsinII; SYNII; SYNIIa; SYNIIb

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Cancer; Neuroscience; Signal Transduction

Purification

Affinity purification

Concentration

2 mg/mL

Dilution

WB 1:1000-1:5000; IHC 1:50-1:200

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

63kDa

Isotype

IgG

UniProtKB · Q92777

Synapsin-2

SYN2_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q92777
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: SYN2
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: —
Processing: —
Secondary accessions: A0A087WW96, A0A087X2E3, A8MY98

Protein keywords

Coding sequence diversity

Alternative splicing

PTM

Phosphoprotein

Technical term

Proteomics identificationReference proteome

Disease

Schizophrenia

Cellular component

Synapse

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MBS2526922-01	SYN2 Polyclonal Antibody
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