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YWHAG Polyclonal Antibody

CAT: 0763-E-AB-12587-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-12587-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways.
Abbreviation
YWHAG
UniProt
P61981
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Synthetic peptide of human YWHAG
Target
14 3 3 gamma;14 3 3 protein gamma;14 3 3 protein gamma subtype;14 3 3gamma;14-3-3 protein gamma;1433G;3 monooxygenase/tryptophan 5 monooxgenase activation protein gamma polypeptide; KCIP 1; KCIP-1; KCIP1; N-terminally processed; Protein kinase C inhibitor protein 1; Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein gamma polypeptide; Ywhag
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Neuroscience; Signal Transduction; Stem Cells
Purification
Affinity purification
Concentration
0.5 mg/mL
Dilution
WB 1:1000-1:5000; IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
28kDa
Isotype
IgG

UniProtKB · P61981

14-3-3 protein gamma

1433G_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P61981
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
YWHAG
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
O70457, P35214, Q6FH52, Q9UDP2, Q9UN99
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Cellular component

CytoplasmMitochondrion

Disease

Disease variantEpilepsy