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14-3-3 beta/alpha Polyclonal Antibody

CAT: 0763-E-AB-12586-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-12586-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene.
Abbreviation
YWHAB
UniProt
P31946
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Synthetic peptide of human YWHAB
Target
14 3 3 alpha;14 3 3 protein beta/alpha;14-3-3 protein beta/alpha;1433B; Brain protein 14 3 3 beta isoform; GW128; HS 1; KCIP-1; KCIP1; N-terminally processed; Protein 1054; Protein kinase C inhibitor protein 1; YWHAA; YWHAB
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Cancer; Cell Biology; Neuroscience; Signal Transduction; Stem Cells
Purification
Affinity purification
Concentration
0.4 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
28kDa
Isotype
IgG

UniProtKB · P31946

14-3-3 protein beta/alpha

1433B_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P31946
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
YWHAB
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A8K9K2, E1P616
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondNitrationPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative initiation

Cellular component

CytoplasmMembraneVacuole

Biological process

Host-virus interaction

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