HSD3B7 Polyclonal Antibody

• Background:

  This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene.

• Abbreviation:

  HSD3B7

• UniProt:

  Q9H2F3

• Host:

  Rabbit

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Recombinant protein of human HSD3B7

• Target:

  3 beta HSD VII;3 beta hydroxy Delta (5) C27 steroid oxidoreductase;3 beta hydroxysteroid dehydrogenase type 7;3 beta hydroxysteroid dehydrogenase type VII; AI195443; BB098564; C (27) 3 beta HSD; Cca2; Cholest 5 ene 3 beta;7 alpha diol 3 beta dehydrogenase; Confluent 3Y1 cell associated 2; Hydroxy delta 5 steroid dehydrogenase;3 beta and steroid delta isomerase 7; OTTMUSP00000018894; OTTMUSP00000018895; OTTMUSP00000018897; PFIC4; SDR11E3

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  IHC

• Field of Research:

  Signal Transduction

• Purification:

  Affinity purification

• Concentration:

  0.3 mg/mL

• Dilution:

  IHC 1:50-1:200

• Buffer:

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Isotype:

  IgG