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FAM107A Polyclonal Antibody

CAT: 0763-E-AB-11213-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-11213-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
FAM107B is a 131 amino acid protein that is encoded by a gene that maps to human chromosome 10, which contains over 800 genes and 135 million nucleotides, making up nearly 4.5% of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. The chromosome 10 encoded gene ERCC6 is important for DNA repair and is linked to Cockayne syndrome which is characterized by extreme photosensitivity and premature aging. Tetrahydrobiopterin deficiency and a number of syndromes involving defective skull and facial bone fusion are also linked to chromosome 10. As with most trisomies, trisomy 10 is rare and is deleterious.
Abbreviation
FAM107A
UniProt
O95990
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant protein of human FAM107A
Target
Down regulated in renal cell carcinoma 1; Down-regulated in renal cell carcinoma 1; Downregulated in renal cell carcinoma; DRR1; F107A; FAM107A; Family with sequence similarity 107; member A; FLJ30158; FLJ45473; Protein FAM107A; Protein TU3A; TU3A
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Cell Biology
Purification
Affinity purification
Concentration
0.7 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · O95990

Actin-associated protein FAM107A

F107A_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O95990
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
FAM107A
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B3KNQ4, B7ZAY5, J3KR61, Q96NH4
Protein keywords

Molecular function

Actin-binding

Coding sequence diversity

Alternative splicing

Biological process

Cell cycleGrowth regulationStress response

Cellular component

Cell junctionCell membraneCell projectionCytoplasmCytoskeletonMembraneNucleusSynapse

Domain

Coiled coil

Technical term

Proteomics identificationReference proteome

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