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DCBLD2 Polyclonal Antibody

CAT: 0763-E-AB-11139-02Size: 60 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-11139-02Size:60 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CLCP1 (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1), also known as DCBLD2 (discoidin, CUB and LCCL domain containing 2) or ESDN, is a 775 amino acid single-pass type I membrane protein that contains one CUB domain, one LCCL domain and one F5/8 type C domain. Expressed at high levels in heart, testis and skeletal muscle, CLCP1 is thought to regulate vascular smooth muscle cell (VSMC) proliferation and remodeling and may be involved in the transformation and metastasis of various cancers, such as metastatic lung cancer and gastric carcinoma.
Abbreviation
DCBLD2
UniProt
Q96PD2
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant protein of human DCBLD2
Target
1700055P21Rik; AW146002; CLCP1; coagulation factor V/VIII-homology domains protein 1; CUB and LCCL domain-containing protein 2; CUB; CUB; LCCL and coagulation factor V/VIII-homology domains protein 1; DCBD2; DCBLD2; Discoidin; discoidin CUB and LCCL domain containing 2; Discoidin; CUB and LCCL domain-containing protein 2; Endothelial and smooth muscle cell-derived neuropilin-like protein; ESDN; LCCL and coagulation factor V/VIII-homology domains protein 1
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Cardiovascular
Purification
Affinity purification
Concentration
0.5 mg/mL
Dilution
IHC 1:100-1:300
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · Q96PD2

Discoidin, CUB and LCCL domain-containing protein 2

DCBD2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q96PD2
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
DCBLD2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
B7WNL1, D3DN41, Q8N6M4, Q8TDX2
Protein keywords

Coding sequence diversity

Alternative splicing

PTM

Disulfide bondGlycoproteinPhosphoprotein

Cellular component

Membrane

Technical term

Proteomics identificationReference proteome

Domain

SignalTransmembraneTransmembrane helix