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PPIB Polyclonal Antibody

CAT: 0763-E-AB-11114-02Size: 60 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-11114-02Size:60 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta.
Abbreviation
PPIB
UniProt
P23284
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant protein of human PPIB
Target
AA408962; AA553318; AI844835; Cphn 2; Cphn2; Cyclophilin B; Cyclophilin like protein; CyP 20b; CYP S1; CYP-S1; CYPB; EC 5.2.1.8; MGC14109; MGC2224; OI9; peptidyl prolyl cis trans isomerase B; Peptidyl prolyl cis trans isomerase B precursor; Peptidyl-prolyl cis-trans isomerase B; peptidylprolyl isomerase B (cyclophilin B) ; Peptidylprolyl isomerase B; PPIase; PPIase B; Ppib; PPIB; Rotamase; Rotamase B; S cyclophilin; S-cyclophilin; SCYLP
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Immunology; Signal Transduction
Purification
Affinity purification
Concentration
0.4 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
24kDa
Isotype
IgG

UniProtKB · P23284

Peptidyl-prolyl cis-trans isomerase B

PPIB_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P23284
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PPIB
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
PPIase B
EC number
5.2.1.8
Processing
Precursor
Secondary accessions
A8K534, Q6IBH5, Q9BVK5
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationGlycoproteinS-nitrosylation

Disease

Disease variantDwarfismOsteogenesis imperfecta

Cellular component

Endoplasmic reticulumVirion

Molecular function

IsomeraseRotamase

Domain

Signal

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