CAST Polyclonal Antibody

• Background:

  The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described.

• Abbreviation:

  CAST

• UniProt:

  P20810

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Recombinant protein of human CAST

• Target:

  BS 17; Calpain inhibitor; Calpastatin; Cast; Heart type calpastatin; ICAL; MGC9402; Sperm BS 17 component; Sperm BS-17 component

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB; IHC

• Field of Research:

  Cancer; Cell Biology; Neuroscience

• Purification:

  Affinity purification

• Concentration:

  0.8 mg/mL

• Dilution:

  WB 1:500-1:2000; IHC 1:100-1:300

• Buffer:

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  77kDa

• Isotype:

  IgG