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OLR1 Polyclonal Antibody

CAT: 0763-E-AB-10934-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-10934-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.
Abbreviation
OLR1
UniProt
P78380
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant protein of human OLR1
Target
C-type lectin domain family 8 member A; CLEC8A; hLOX 1; hLOX-1; Lectin like oxidized LDL receptor 1; Lectin like oxLDL receptor 1; Lectin type oxidized LDL receptor 1; Lectin-like oxidized LDL receptor 1; Lectin-like oxLDL receptor 1; Lectin-type oxidized LDL receptor 1; low density lipoprotein oxidized; receptor 1; LOX-1; LOXIN; Olr1; OLR1; Ox LDL receptor 1; Ox-LDL receptor 1; Oxidised low density lipoprotein (lectin like) receptor 1; Oxidized low density lipoprotein receptor 1; Oxidized low density lipoprotein receptor 1 soluble form; Oxidized low-density lipoprotein receptor 1; SCARE1; Scavenger receptor class E; member 1; SLOX1; soluble form; SR-EI
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Cardiovascular; Metabolism
Purification
Affinity purification
Concentration
0.5 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · P78380

Oxidized low-density lipoprotein receptor 1

OLR1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P78380
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
OLR1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
Ox-LDL receptor 1
EC number
—
Processing
—
Secondary accessions
A8K7V9, B4DI48, G3V1I4, Q2PP00, Q7Z484
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

Cell adhesionImmunityInflammatory response

Cellular component

Cell membraneMembraneSecreted

Domain

Coiled coilSignal-anchorTransmembraneTransmembrane helix

PTM

Disulfide bondGlycoproteinLipoproteinPalmitate

Ligand

Lectin

Molecular function

Receptor

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