ALKBH2 Polyclonal Antibody

• Background :

  The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine. Dioxygenase that repairs alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. Can also repair alkylated DNA containing 1-ethenoadenine (in vitro) . Has strong preference for double-stranded DNA. Has low efficiency with single-stranded substrates. Requires molecular oxygen, alpha-ketoglutarate and iron.

• Abbreviation :

  ALKBH2

• UniProt :

  Q6NS38

• Host :

  Rabbit

• Reactivity :

  Human; Mouse

• Immunogen :

  Recombinant protein of human ALKBH2

• Target :

  2OG Fe (II) oxy DC1;9530023G02; ABH 2; ABH2; alkB alkylation repair homolog 2; ALKB2; ALKBH2 alkB; ALKBH2; Alkylated DNA repair protein alkB homolog; Alkylated DNA repair protein alkB homolog 2; Alkylation repair homolog 2; Alpha ketoglutarate dependent dioxygenase alkB homolog 2; Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2; AU016977; DNA oxidative demethylase ALKBH2; EC 1.14.11.; FLJ99103; hABH2; mABH2; MGC90512; Oxy DC1

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Applications :

  WB

• Field of Research :

  Epigenetics and Nuclear Signaling

• Purification :

  Affinity purification

• Concentration :

  0.3 mg/mL

• Dilution :

  WB 1:500-1:2000

• Buffer :

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Shipping Conditions :

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  29kDa

• Isotype :

  IgG