MAP2K6 Polyclonal Antibody

CAT: 0763-E-AB-10446-02Size: 60 µLDry Ice: NoHazardous: No

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CAT#:0763-E-AB-10446-02Size:60 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.

Abbreviation

MAP2K6

UniProt

P52564

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Recombinant protein of human MAP2K6

Target

Dual specificity mitogen activated protein kinase kinase 6; Dual specificity mitogen-activated protein kinase kinase 6; MAP kinase kinase 6; MAP2K6; MAPK/ERK kinase 6; MAPKK 6; MAPKK6; MEK 6; MEK6; Mitogen Activated Protein Kinase Kinase 6; MKK 6; MKK6; MP2K6; PRKMK6; Protein kinase mitogen activated kinase 6; protein kinase; mitogen-activated; kinase 6 (MAP kinase kinase 6) ; SAPK kinase 3; SAPKK-3; SAPKK3; SKK3; Stress-activated protein kinase kinase 3

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Cell Biology; Immunology; Signal Transduction

Purification

Affinity purification

Concentration

0.3 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:25-1:100

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

37kDa

Isotype

IgG

UniProtKB · P52564

Dual specificity mitogen-activated protein kinase kinase 6

MP2K6_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P52564
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: MAP2K6
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: MAP kinase kinase 6, MAPKK 6
EC number: 2.7.12.2
Processing: —
Secondary accessions: —

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Biological process

ApoptosisStress responseTranscriptionTranscription regulation

Ligand

ATP-bindingNucleotide-binding

Cellular component

CytoplasmCytoskeletonNucleus

Molecular function

KinaseSerine/threonine-protein kinaseTransferaseTyrosine-protein kinase

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Alternative Products

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MBS126802-01	MAP2K6 Polyclonal Antibody
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