FITC Anti-Mouse IL-10 Antibody[JES5-16E3]

• Background:

  IL-10 was originally described as Cytokine Synthesis Inhibitory Factor (CSIF) by virtue of its ability to inhibit cytokine production by Th1 clones. IL-10 shares over 80% sequence homology with the Epstein-Barr virus protein BCRFI. IL-10 inhibits IFN-γ, TNF-β, and IL-2 production by Th1 clones; inhibits macrophage-mediated IL-1, IL-6, and TNF-α synthesis; suppresses the delayed type hypersensitivity response; stimulates Th2 cell response (which results in elevated antibody production) ; and promotes mast cell proliferation in combination with IL-4.

• Abbreviation:

  IL-10

• Gene ID:

  16153

• UniProt:

  P18893

• Host:

  Rat

• Reactivity:

  Mouse

• Target:

  CSIF; Cytokine synthesis inhibitory factor; IL-10; Interleukin-10

• Clonality:

  Monoclonal

• Clone:

  JES5-16E3

• Conjugation:

  FITC

• Applications:

  ICFCM

• Field of Research:

  Immunology

• Concentration:

  5 μL/Test

• Buffer:

  Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

• Citation 01:

  https://onlinelibrary.wiley.com/doi/abs/10.1002/cam4.70147

• Recommended Usage:

  The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

• Isotype:

  Rat IgG2b, κ