Elab Fluor® Red 780 Anti-Mouse CD45 Antibody[30-F11]

• Background:

  CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets. There are different isoforms of CD45 that arise from alternative splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.

• Abbreviation:

  CD45

• Gene ID:

  19264

• UniProt:

  P06800

• Host:

  Rat

• Reactivity:

  Mouse

• Target:

  CD45; L-CA; Ly-5; Ptprc; Receptor-type tyrosine-protein phosphatase C; T200

• Clonality:

  Monoclonal

• Clone:

  30-F11

• Conjugation:

  Elab Fluor®Red 780

• Applications:

  FCM

• Field of Research:

  Cell Biology; Immunology; Inhibitory Molecules; Innate Immunity; Neuroscience; Neuroscience Cell Markers; Stem Cells

• Concentration:

  5 μL/Test

• Buffer:

  Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

• Citation 01:

  https://www.cell.com/cell-metabolism/abstract/S1550-4131(24)00181-5

• Citation 02:

  https://www.sciencedirect.com/science/article/pii/S1385894725002256

• Citation 03:

  https://link.springer.com/article/10.1186/s13073-025-01465-1

• Citation 04:

  https://pubs.acs.org/doi/abs/10.1021/acsami.4c10363

• Citation 05:

  https://aacrjournals.org/cancerimmunolres/article/doi/10.1158/2326-6066.CIR-23-0595/734884

• Citation 06:

  https://www.hindawi.com/journals/omcl/2023/2894695/

• Recommended Usage:

  The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

• Isotype:

  Rat IgG2b, κ