Elab Fluor® 488 Anti-Mouse CD103 Antibody[M290]

• Background:

  CD103 is a type I transmembrane glycoprotein known as αE integrin or Integrin αIEL chain. It belongs to the integrin family and is primarily found on intestinal intraepithelial lymphocytes (IEL) . CD103 is also expressed on a subpopulation of lamina propria T cells, epithelial dendritic cells, lamina propria-derived dendritic cells, and a small subset of peripheral lymphocytes. T regulatory cells express high level of CD103. The CD103 expression on lymphocytes can be induced upon activation and TGF-β stimulation. In association with integrin β7, CD103 is expressed as αE/β7 heterodimer. Mature CD103 protein can be cleaved into 2 chains, a 150 kD (C-terminal) chain and a 25 kD (N-terminal) chain, which remain linked by disulfide bonds. CD103 binds to E-cadherin and mediates homing of lymphocytes to the intestinal epithelium.

• Abbreviation:

  CD103

• Gene ID:

  16407

• UniProt:

  Q60677

• Host:

  Rat

• Reactivity:

  Mouse

• Target:

  CD103; Integrin alpha M290; Integrin alpha-E; Itgae

• Clonality:

  Monoclonal

• Clone:

  M290

• Conjugation:

  Elab Fluor®488

• Applications:

  FCM

• Field of Research:

  Immunology

• Concentration:

  0.5 mg/mL

• Buffer:

  Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

• Recommended Usage:

  6

• Isotype:

  Rat IgG2a, κ