PB-119

• UNSPSC Description:

  PB-119 is a PEGylated Exenatide. PB-119 decreases glycemic levels by improving beta-cell function and insulin resistance. PB-119 can be used for research of type 2 diabetes[1].

• Target Antigen:

  Others

• Type:

  Peptides

• Related Pathways:

  Others

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/pb-119.html

• Solubility:

  10 mM in DMSO

• Smiles:

  [Asp-Phe-Val-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-{Cys(PEG23K)}-NH2]

• Molecular Weight:

  28000 (Approximately)

• References & Citations:

  [1]Liu X, et al. PEGylated exenatide injection (PB-119) improves beta-cell function and insulin resistance in treatment-naïve type 2 diabetes mellitus patients. Front Pharmacol. 2023 Sep 14;14:1088670.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  Phase 2