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Tricetin

CAT: 0804-HY-131592-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-131592-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tricetin is a potent competitive inhibitor of the Keap1-Nrf2 Protein Protein Interaction (PPI) . Tricetin protects against 6-OHDA-induced neurotoxicity in Parkinson's disease model by activating Nrf2/HO-1 signaling pathway and preventing mitochondria-dependent apoptosis pathway[1].
CAS Number
520-31-0
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Apoptosis; Keap1-Nrf2
Type
Natural Products
Related Pathways
Apoptosis; NF-κB
Applications
Neuroscience-Neurodegeneration
Field of Research
Cancer; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/tricetin.html
Purity
99.19
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C1C=C(C2=CC(O)=C(O)C(O)=C2)OC3=CC(O)=CC(O)=C13
Molecular Formula
C15H10O7
Molecular Weight
302.24
Precautions
H315, H319, H335
References & Citations
[1]Ren J, et al. Tricetin protects against 6-OHDA-induced neurotoxicity in Parkinson's disease model by activating Nrf2/HO-1 signaling pathway and preventing mitochondria-dependent apoptosis pathway. Toxicol Appl Pharmacol. 2019;378:114617.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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