Flavanone (Standard)

• Description :

  Flavanone (Standard) is the analytical standard of Flavanone. This product is intended for research and analytical applications. Flavanone is a naturally occurring flavone. Flavanone has inhibitory activity for human estrogen synthetase (aromatase) . lavanone is the inhibitor for ERK/p38/NF-κB signaling pathway. Flavanone exhibits oral activity and antitumor efficacy[1][2].

• UNSPSC :

  12352005

• Target :

  Cytochrome P450; ERK; MMP; NF-κB; p38 MAPK; PAI-1; Reference Standards

• Type :

  Reference Standards

• Related Pathways :

  MAPK/ERK Pathway; Metabolic Enzyme/Protease; NF-κB; Others; Stem Cell/Wnt

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/flavanone-standard.html

• Smiles :

  O=C1CC(C2=CC=CC=C2)OC3=CC=CC=C13

• Molecular Formula :

  C15H12O2

• Molecular Weight :

  224.25

• References & Citations :

  [1]JT Kellis Jr, et al. Inhibition of human estrogen synthetase (aromatase) by flavones. Science. 1984 Sep. 225 (4666) :1032-1034.|[2]Hsiao YC, et al., Flavanone and 2'-OH flavanone inhibit metastasis of lung cancer cells via down-regulation of proteinases activities and MAPK pathway. Chem Biol Interact. 2007 May 1;167 (3) :193-206.|[3]Hsiao YC, et al., The tumor-growth inhibitory activity of flavanone and 2'-OH flavanone in vitro and in vivo through induction of cell cycle arrest and suppression of cyclins and CDKs. J Biomed Sci. 2007 Jan;14 (1) :107-19.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference Standards

• CAS Number :

  [487-26-3]