N-Acetyl-Ile-Glu-Pro-Asp-p-nitroanilide

N-Acetyl-Ile-Glu-Pro-Asp-p-nitroanilide

• CAS Number: 216757-29-8
• UNSPSC Description: N-Acetyl-Ile-Glu-Pro-Asp-p-nitroanilide (Ac-IEPD-pNA) is a granzyme B substrate that allows accurate measurement of granzyme B activity[1].
• Target Antigen: Fluorescent Dye
• Type: Peptides
• Related Pathways: Others
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/n-acetyl-ile-glu-pro-asp-p-nitroanilide.html
• Purity: 98.52
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: CC[C@H](C)[C@H](NC(C)=O)C(N[C@@H](CCC(O)=O)C(N1[C@@H](CCC1)C(N[C@@H](CC(O)=O)C(NC2=CC=C(C=C2)[N+]([O-])=O)=O)=O)=O)=O
• Molecular Weight: 634.63
• References & Citations: [1]Kristina Fritsch, et al. Suppression of granzyme B activity and caspase-3 activation in leukaemia cells constitutively expressing the protease inhibitor 9. Ann Hematol. 2013 Dec;92(12):1603-9.
• Shipping Conditions: Blue Ice
• Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
• Clinical Information: No Development Reported