N-Acetyl-Ile-Glu-Pro-Asp-p-nitroanilide

• UNSPSC Description:

  N-Acetyl-Ile-Glu-Pro-Asp-p-nitroanilide (Ac-IEPD-pNA) is a granzyme B substrate that allows accurate measurement of granzyme B activity[1].

• Target Antigen:

  Fluorescent Dye

• Type:

  Peptides

• Related Pathways:

  Others

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/n-acetyl-ile-glu-pro-asp-p-nitroanilide.html

• Purity:

  98.52

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  CC[C@H](C)[C@H](NC(C)=O)C(N[C@@H](CCC(O)=O)C(N1[C@@H](CCC1)C(N[C@@H](CC(O)=O)C(NC2=CC=C(C=C2)[N+]([O-])=O)=O)=O)=O)=O

• Molecular Weight:

  634.63

• References & Citations:

  [1]Kristina Fritsch, et al. Suppression of granzyme B activity and caspase-3 activation in leukaemia cells constitutively expressing the protease inhibitor 9. Ann Hematol. 2013 Dec;92(12):1603-9.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)

• Clinical Information:

  No Development Reported

• CAS Number:

  216757-29-8