Remdesivir O-desphosphate acetonide impurity

Remdesivir O-desphosphate acetonide impurity

• CAS Number: 1191237-80-5
• UNSPSC Description: Remdesivir O-desphosphate acetonide impurity is an impurity of Remdesivir. Remdesivir (GS-5734), a nucleoside analogue with effective antiviral activity and is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro[1][2].
• Target Antigen: DNA/RNA Synthesis; SARS-CoV
• Type: Reference compound
• Related Pathways: Anti-infection;Cell Cycle/DNA Damage
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/remdesivir-o-desphosphate-acetonide-impurity.html
• Smiles: N#C[C@](O1)(C2=CC=C3N2N=CN=C3N)[C@@](OC4(C)C)([H])[C@@](O4)([H])[C@H]1CO
• Molecular Weight: 331.332
• References & Citations: [1]Dustin Siegel, et al. Discovery and Synthesis of a Phosphoramidate Prodrug of a Pyrrolo[2,1-f][triazin-4-amino] Adenine C-Nucleoside (GS-5734) for the Treatment of Ebola and Emerging Viruses. J Med Chem. 2017 Mar 9;60(5):1648-1661.|[2]Manli Wang, et al. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro. Cell Res. 2020 Mar;30(3):269-271.
• Shipping Conditions: Room Temperature