Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp

CAT:
804-HY-P10461-01
Size:
5 mg

For Laboratory Research Only. Not for Clinical or Personal Use.

  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp - image 1

Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp

  • UNSPSC Description:

    Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp is a fluorescence-quenched peptide substrate for human proteinase 3 (kcat/Km = 1,570 mM-1s-1), and can be used for detection of proteinase 3 (PR3) activity[1][2].
  • Target Antigen:

    Others
  • Type:

    Peptides
  • Related Pathways:

    Others
  • Field of Research:

    Others
  • Assay Protocol:

    https://www.medchemexpress.com/abz-val-ala-asp-nva-arg-asp-arg-gln-eddnp.html
  • Purity:

    99.65
  • Solubility:

    DMSO : 100 mg/mL (ultrasonic)
  • Smiles:

    O=C([C@H](CCC(N)=O)NC([C@H](CCCNC(N)=N)NC([C@H](CC(O)=O)NC([C@H](CCCNC(N)=N)NC([C@@H](NC([C@H](CC(O)=O)NC([C@H](C)NC([C@H](C(C)C)NC(C1=CC=CC=C1N)=O)=O)=O)=O)CCC)=O)=O)=O)=O)NCCNC2=CC=C(C=C2[N+]([O-])=O)[N+]([O-])=O
  • Molecular Weight:

    1285.33
  • References & Citations:

    [1]Yu J, et al. Cathepsin C from extracellular histone-induced M1 alveolar macrophages promotes NETosis during lung ischemia-reperfusion injury. Redox Biol. 2024 Jun 6;74:103231. |[2]Korkmaz B, et al. Measurement of neutrophil elastase, proteinase 3, and cathepsin G activities using intramolecularly quenched fluorogenic substrates. Methods Mol Biol. 2012;844:125-38.
  • Shipping Conditions:

    Blue Ice
  • Storage Conditions:

    -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
  • Clinical Information:

    No Development Reported
  • CAS Number:

    1042405-14-0