Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp

Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp

• CAS Number: 1042405-14-0
• UNSPSC Description: Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp is a fluorescence-quenched peptide substrate for human proteinase 3 (kcat/Km = 1,570 mM-1s-1), and can be used for detection of proteinase 3 (PR3) activity[1][2].
• Target Antigen: Others
• Type: Peptides
• Related Pathways: Others
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/abz-val-ala-asp-nva-arg-asp-arg-gln-eddnp.html
• Purity: 99.65
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: O=C([C@H](CCC(N)=O)NC([C@H](CCCNC(N)=N)NC([C@H](CC(O)=O)NC([C@H](CCCNC(N)=N)NC([C@@H](NC([C@H](CC(O)=O)NC([C@H](C)NC([C@H](C(C)C)NC(C1=CC=CC=C1N)=O)=O)=O)=O)CCC)=O)=O)=O)=O)NCCNC2=CC=C(C=C2[N+]([O-])=O)[N+]([O-])=O
• Molecular Weight: 1285.33
• References & Citations: [1]Yu J, et al. Cathepsin C from extracellular histone-induced M1 alveolar macrophages promotes NETosis during lung ischemia-reperfusion injury. Redox Biol. 2024 Jun 6;74:103231. |[2]Korkmaz B, et al. Measurement of neutrophil elastase, proteinase 3, and cathepsin G activities using intramolecularly quenched fluorogenic substrates. Methods Mol Biol. 2012;844:125-38.
• Shipping Conditions: Blue Ice
• Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
• Clinical Information: No Development Reported