Products for Research Use Only
RegisterLogin

RecombinantVEGF165, Human

CAT: 0013-GTR18990189-01Size: 10 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR18990189-01Size:10 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Vascular Endothelial Growth Factor (VEGF) is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, Vascular Endothelial Growth Factor (VEGF) plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates Vascular Endothelial Growth Factor (VEGF) in the induction of tumor metastasis and intra-ocular neovascular syndromes. Vascular Endothelial Growth Factor (VEGF) signals through the three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product.Recombinant human Vascular Endothelial Growth Factor A165 (rhVEGF-A165) produced in Pichia pastoris is a disulfide-linked homodimer containing two polypeptide chains of 165 amino acids each. A fully biologically active molecule, rhVEGF-A165 has a molecular mass of 38.2kDa analyzed by non-reducing SDS-PAGE and is obtained by chromatographic techniques at GenScript.
Product Name Alternative
Vascular Endothelial Growth Factor, VPF, Folliculostellate cell-derived growth factor, Glioma-derived endothelial cell mitogen
Source
P. pastoris
Endotoxin
< 0.5 EU/μg, determined by LAL method.
Purity
> 95% as analyzed by reducing SDS-PAGE.
Bioactivity
ED50 of 1-5ng/ml, measured by the dose-dependent stimulation of the proliferation of HUVEC cells, corresponding to a specific activity of 2x 10ˆ5-1x 10ˆ6 units/mg.
Form
Lyophilized after extensive dialysis against 25 mM HEPES and 150 mM NaCl, pH 7.0.
Molecular Weight
38.2kDa, observed by non-reducing SDS-PAGE
Storage Conditions
Lyophilized recombinant human Vascular Endothelial Growth Factor A165 (rhVEGF-A165) remains stable up to 12 months at -80°C from date of receipt. Upon reconstitution, rhVEGF-A165 should be stable up to 4 week at 4°C or up to 6 months at -20°C.
Notes
For research use only.
Applications Notes
Reconstituted in ddH2O at 100 μg/ml.
Preservative
Lyophilized after extensive dialysis against 25 mM HEPES and 150 mM NaCl, pH 7.0.
AA Sequence
APMAEG GGQNHHEVVK FMDVYQRSYC HPIETLVDIF QEYPDEIEYI FKPSCVPLMR CGGCCNDEGL ECVPTEESNI TMQIMRIKPH QGQHIGEMSF LQHNKCECRP KKDRARQENP CGPCSERRKH LFVQDPQTCK CSCKNTDSRC KARQLELNER TCRCDKPRR

Related Products

CatalogName
GTR18990248-01RecombinantVEGF165, Rat (CHO-expressed)
GTR18990449-01RecombinantVEGF121, Human
GTR18990191-01RecombinantVEGF164, Mouse (P.pastoris-expressed)
GTR18777889-01Human Human CYP19A1 Antibody
GTR18882498-01Human human Septin-7 protein
GTR18880605-01Human Human Septin-7 protein
GTR18834069-01Human Human Macrosialin ELISA Kit
GTR19008890-01Human BDNF (BDNF Human) protein
GTR18698434-01HuMax-IL8 Human Monoclonal Antibody
GTR18698323-01HuMax-IL15 Human Monoclonal Antibody

Alternative Products

CatalogName
BK0352RecombinantVEGF165,Human
BK0352-01RecombinantVEGF165, Human
BK0335RecombinantVEGF165,Human(HEK293-expressed)
BK0335-01RecombinantVEGF165, Human (HEK293-expressed)
BK0293-01RecombinantVEGF165, Rat (CHO-expressed)
BK0293RecombinantVEGF165,Rat(CHO-expressed)
P83251PMG36e-ADH1B (human-opt-human) -ALDH2 (human-opt-human)
P81559PCMV-Twinstrep-UFM1 (human) -UFM1 (human-opt-human) -UFM1 (human-opt-human) -Neo
9230-10Human CellExp™ Human CD40/ TNFRSF5, Human recombinant
P1493-200Human CellExp™ Human Serum Albumin, Human Recombinant

Popular Products