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Purfalcamine

CAT: 0804-HY-117015-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-117015-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Purfalcamine is an orally active, selective Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1) inhibitor with an IC50 of 17 nM and an EC50 of 230 nM. Purfalcamine has antimalarial activity and causes malaria parasites developmental arrest at the schizont stage[1][2].
CAS Number
1038620-68-6
Product Name Alternative
Y-39992
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/purfalcamine.html
Purity
99.44
Solubility
DMSO : 12.5 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=C(NC2=C3N=CN(C4=CC=CC(F)=C4)C3=NC(N[C@H]5CC[C@H](N)CC5)=N2)C=C1)N6CCCCC6
Molecular Formula
C29H33FN8O
Molecular Weight
528.62
References & Citations
Plasmodium falciparumToxoplasma gondii
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Plasmodium; Toxoplasma

Alternative Products

CatalogName
MBS5802658Purfalcamine

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