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Purfalcamine

CAT: 0931-T38269-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T38269-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1038620-68-6
Target
Others, Parasite
Related Pathways
Microbiology/Virology, Others
Bioactivity
Purfalcamine is an orally active, selective Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1) inhibitor with an IC50 of 17 nM and an EC50 of 230 nM, exhibiting antimalarial activity by inducing developmental arrest of malaria parasites at the schizont stage[1][2].
Smiles
N[C@H]1CC[C@@H](CC1)Nc1nc(Nc2ccc(cc2)C(=O)N2CCCCC2)c2ncn(-c3cccc(F)c3)c2n1
Molecular Formula
C29H33FN8O
Molecular Weight
528.62
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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