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CCKBR rabbit pAb

CAT: 0855-ES20790-01Size: 50 µLDry Ice: NoHazardous: No
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Background
This gene encodes a G-protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. Alternative splicing results in multiple transcript variants. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors. [provided by RefSeq, Dec 2015]
Description
This gene encodes a G-protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. Alternative splicing results in multiple transcript variants. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors. [provided by RefSeq, Dec 2015],
Product Name Alternative
CCKBR; CCKRB; Gastrin/cholecystokinin type B receptor; CCK-B receptor; CCK-BR; Cholecystokinin-2 receptor; CCK2-R
UniProt
P32239
Swiss Prot
P32239
Reactivity
Human; Rat; Mouse
Immunogen
Synthetic Peptide of CCKBR AA range: 306-356
Target
CCKBR
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:1000-2000
Buffer
-20°C/1 year
Molecular Weight
50kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
50kD
Fragment
IgG
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Other Product Names
CCKBR; CCKRB; Gastrin/cholecystokinin type B receptor; CCK-B receptor; CCK-BR; Cholecystokinin-2 receptor; CCK2-R
Gene ID (Human)
887

UniProtKB · P32239

Gastrin/cholecystokinin type B receptor

GASR_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P32239
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CCKBR
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
CCK-B receptor, CCK-BR
EC number
—
Processing
—
Secondary accessions
A8K7P9, O75824, Q16144, Q92492, Q96LC6, Q9NYK7, Q9UBV1
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneMembrane

PTM

Disulfide bondGlycoproteinLipoproteinPalmitate

Molecular function

G protein-coupled receptorReceptorTransducer

Domain

TransmembraneTransmembrane helix

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