9 (S) -HpOTrE

CAT: 0804-HY-131310-01Size: 500 µgDry Ice: NoHazardous: No

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CAT#:0804-HY-131310-01Size:500 µg

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Description

9 (S) -HpOTrE is a monohydroperoxy polyunsaturated fatty acid produced by the action of 5-lipoxygenase (5-LO) on α-linolenic acid. It can be further metabolized to colnelenic acid by a divinyl ether synthase activity found in garlic and potato microsomal fractions. 9 (S) -HpOTrE also serves as a substrate for further oxidation by both soybean and potato LOs, resulting in the formation of 9,16-dihydroperoxy acid.The suicide inactivation of LOs when 9 (S) -HpOTrE is used as a substrate is thought to occur via formation of an unstable epoxide.

CAS Number

111004-08-1

UNSPSC

12352211

Hazard Statement

H302-H315-H319-H335

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/9-s-hpotre.html

Smiles

CC/C=C\C/C=C\C=C\[C@@H](OO)CCCCCCCC(O)=O

Molecular Formula

C18H30O4

Molecular Weight

310.43

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Galliard, et al. Lipoxygenase from potato tubers. Partial purification and properties of an enzyme that specifically oxygenates the 9-position of linoleic acid. Biochem. J. 124, 431-438 (1971) .

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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9 (S) -HpOTrE

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