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SAINT-2

CAT: 0804-HY-158705Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-158705Size:1 Each
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Description
SAINT-2 is a cationic lipid with gene transfection activity and is a pyridyl lipid analog. Molecular membranes prepared by SAINT-2 can interact with plasmids to form lipid complexes. After the complex is taken up by cells, the plasmid dissociates from the lipid complex under the action of DOPE and the plasmid translocates across the endosome and/or nuclear membrane. Thus, SAINT-2 effectively transfers small oligonucleotides into cells[1].
CAS Number
187587-97-9
UNSPSC
12352005
Target
Liposome
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/saint-2.html
Smiles
CCCCCCCC/C=C\CCCCCCCCC(C1=CC=[N+](C)C=C1)CCCCCCCC/C=C\CCCCCCCC.[Cl-]
Molecular Formula
C43H78ClN
Molecular Weight
644.54
References & Citations
[1]Zuhorn IS, et al. Phase behavior of cationic amphiphiles and their mixtures with helper lipid influences lipoplex shape, DNA translocation, and transfection efficiency. Biophys J. 2002 Oct;83 (4) :2096-108.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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