Anti-CD11C (8E3) monoclonal ITGAX Antibody

• Description:

  Boster Bio Anti-CD11C (8E3) monoclonal ITGAX Antibody catalog # M00357-2. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

• Synonyms:

  Integrin alpha-X; CD11 antigen-like family member C; Leu M5; Leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; CD11c; ITGAX; CD11C;

• Gene Name:

  ITGAX

• UniProt:

  P20702

• Host:

  Mouse

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthetic peptide, corresponding to amino acids of Human CD11C

• Clonality:

  Monoclonal

• Tissue Specificity:

  Predominantly expressed in monocytes and granulocytes.

• Applications:

  WB

• Purification:

  The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Dilution:

  WB: 1:500-1:2000

• Form:

  Liquid

• Function:

  Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.

• Molecular Weight:

  127829 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Other Gene Names:

  Integrin alpha-X

• Subcellular Location:

  Membrane; Single-pass type I membrane protein.

• Protein Name:

  Integrin alpha-X