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Anti-SETD6 Antibody

CAT: 0519-A08952Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0519-A08952Size:100 µL
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Description
Boster Bio Anti-SETD6 Antibody catalog # A08952. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Synonyms
N-lysine methyltransferase SETD6;2.1.1.-; SET domain-containing protein 6; SETD6;
Gene Name
SETD6
UniProt
Q8TBK2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human SETD6 (NP_001153777.1) .
Clonality
Polyclonal
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:2000
Form
Liquid
Function
Protein-lysine N-methyltransferase. Monomethylates 'Lys- 310' of the RELA subunit of NF-kappa-B complex, leading to down- regulate NF-kappa-B transcription factor activity (PubMed:21131967) . Monomethylates 'Lys-8' of H2AZ (H2AZK8me1) (PubMed:23324626) . Required for the maintenance of embryonic stem cell self-renewal (By similarity) .
Molecular Weight
53189 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
N-lysine methyltransferase SETD6
Subcellular Location
Nucleus
Protein Name
N-lysine methyltransferase SETD6

UniProtKB · Q8TBK2

N-lysine methyltransferase SETD6

SETD6_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q8TBK2
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SETD6
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.1.1.-
Processing
—
Secondary accessions
A8K380, B5ME38, Q9H787
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

PTM

Methylation

Molecular function

MethyltransferaseTransferase

Cellular component

Nucleus

Ligand

S-adenosyl-L-methionine