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Anti-CHST2 Antibody

CAT: 0519-A08119-1Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0519-A08119-1Size:100 µL
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Description
Boster Bio Anti-CHST2 Antibody catalog # A08119-1. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Synonyms
Carbohydrate sulfotransferase 2;2.8.2.-; Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 2; GST-2; N-acetylglucosamine 6-O-sulfotransferase 1; GlcNAc6ST-1; Gn6ST-1; CHST2; GN6ST;
Gene Name
CHST2
UniProt
Q9Y4C5
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding Human CHST2.
Clonality
Polyclonal
Tissue Specificity
Widely expressed. Highly expressed in bone marrow, peripheral blood leukocytes, spleen, brain, spinal cord, ovary and placenta. Expressed by high endothelial cells (HEVs) and leukocytes.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:1000
Form
Liquid
Function
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues within keratan-like structures on N-linked glycans and within mucin-associated glycans that can ultimately serve as SELL ligands. SELL ligands are present in high endothelial cells (HEVs) and play a central role in lymphocyte homing at sites of inflammation. Participates in biosynthesis of the SELL ligand sialyl 6-sulfo Lewis X and in lymphocyte homing to Peyer patches. Has no activity toward O-linked sugars. Its substrate specificity may be influenced by its subcellular location. Sulfates GlcNAc residues at terminal, non-reducing ends of oligosaccharide chains.
Molecular Weight
57857 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Carbohydrate sulfotransferase 2
Subcellular Location
Golgi apparatus, trans-Golgi network membrane
Protein Name
Carbohydrate sulfotransferase 2

UniProtKB · Q9Y4C5

Carbohydrate sulfotransferase 2

CHST2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9Y4C5
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CHST2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.8.2.-
Processing
—
Secondary accessions
D3DNG5, Q2M370, Q9GZN5, Q9UED5, Q9Y6F2
Protein keywords

Coding sequence diversity

Alternative initiation

Biological process

Carbohydrate metabolismInflammatory response

PTM

Disulfide bondGlycoprotein

Cellular component

Golgi apparatusMembrane

Technical term

Proteomics identificationReference proteome

Domain

Signal-anchorTransmembraneTransmembrane helix

Molecular function

Transferase

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