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Anti-SMARCD2 Antibody

CAT: 0519-A08109Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0519-A08109Size:100 µL
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Description
Boster Bio Anti-SMARCD2 Antibody catalog # A08109. Tested in WB, IHC applications. This antibody reacts with Human, Mouse.
Synonyms
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2;60 kDa BRG-1/Brm-associated factor subunit B; BRG1-associated factor 60B; BAF60B; SMARCD2; BAF60B; PRO2451;
Gene Name
SMARCD2
UniProt
Q92925
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human SMARCD2 (NP_001091896.1) .
Clonality
Polyclonal
Tissue Specificity
Isoform 2 is expressed in the pancreas.
Applications
WB, IHC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology) . Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner (PubMed:22952240, PubMed:26601204) . Critical regulator of myeloid differentiation, controlling granulocytopoiesis and the expression of genes involved in neutrophil granule formation (PubMed:28369036) .
Molecular Weight
58921 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2
Subcellular Location
Nucleus .
Protein Name
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2

UniProtKB · Q92925

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2

SMRD2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q92925
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SMARCD2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A5PLL5, A6NNQ7, B4DV56, B4E1R6, Q7L2I6, Q9UHZ1
Protein keywords

Coding sequence diversity

Alternative splicing

Molecular function

Chromatin regulator

PTM

Isopeptide bondMethylationPhosphoproteinUbl conjugation

Cellular component

Nucleus

Technical term

Proteomics identificationReference proteome

Biological process

TranscriptionTranscription regulation

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