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Anti-GCC2 Antibody

CAT: 0519-A07107-1Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0519-A07107-1Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Anti-GCC2 Antibody tested in WB, reactive to human
Synonyms
GRIP and coiled-coil domain-containing protein 2;185 kDa Golgi coiled-coil protein; GCC185; CLL-associated antigen KW-11; CTCL tumor antigen se1-1; Ran-binding protein 2-like 4; RanBP2L4; Renal carcinoma antigen NY-REN-53; GCC2; KIAA0336, RANBP2L4;
Gene Name
GCC2
UniProt
Q8IWJ2
Host
Rabbit
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human GCC2
Clonality
Polyclonal
Tissue Specificity
Ubiquitous.
Applications
WB
Field of Research
G Protein Signaling, Golgi Proteins, Protein Trafficking, Ras Family, Signal Transduction, Signaling Pathway, Small G Proteins, Vesicle Transport
Concentration
0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Function
Golgin which probably tethers transport vesicles to the trans-Golgi network (TGN) and regulates vesicular transport between the endosomes and the Golgi. As a RAB9A effector it is involved in recycling of the mannose 6-phosphate receptor from the late endosomes to the TGN. May also play a role in transport between the recycling endosomes and the Golgi. Required for maintenance of the Golgi structure, it is involved in the biogenesis of noncentrosomal, Golgi-associated microtubules through recruitment of CLASP1 and CLASP2.
Molecular Weight
195910 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
GRIP and coiled-coil domain-containing protein 2
Subcellular Location
Cytoplasm. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein.

UniProtKB · Q8IWJ2

GRIP and coiled-coil domain-containing protein 2

GCC2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q8IWJ2
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
GCC2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A6H8X8, O15045, Q4ZG46, Q8TDH3, Q9H2G8
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Domain

Coiled coil

Cellular component

CytoplasmGolgi apparatusMembrane

Biological process

Protein transportTransport

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