Anti-Interferon lambda-1 IFNL1 Antibody

• Description:

  Boster Bio Anti-Interferon lambda-1 IFNL1 Antibody catalog # A07060-1. Tested in WB, IHC-P applications. This antibody reacts with Human, Rat, Mouse.

• Synonyms:

  Interferon lambda-1; IFN-lambda-1; Cytokine Zcyto21; Interleukin-29; IL-29; IFNL1; IL29, ZCYTO21;

• Gene Name:

  IFNL1

• UniProt:

  Q8IU54

• Host:

  Rabbit

• Reactivity:

  Human, Rat, Mouse

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 20-200 of human IFNL1 (NP_742152.1) .

• Clonality:

  Polyclonal

• Applications:

  WB, IHC-P

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Form:

  Liquid

• Function:

  Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN- stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type- selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.

• Molecular Weight:

  21898 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Other Gene Names:

  Interferon lambda-1

• Subcellular Location:

  Secreted.

• Protein Name:

  Interferon lambda-1