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Anti-Interferon lambda-1 IFNL1 Antibody

CAT: 0519-A07060-1Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0519-A07060-1Size:100 µL
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Description
Boster Bio Anti-Interferon lambda-1 IFNL1 Antibody catalog # A07060-1. Tested in WB, IHC-P applications. This antibody reacts with Human, Rat, Mouse.
Synonyms
Interferon lambda-1; IFN-lambda-1; Cytokine Zcyto21; Interleukin-29; IL-29; IFNL1; IL29, ZCYTO21;
Gene Name
IFNL1
UniProt
Q8IU54
Host
Rabbit
Reactivity
Human, Rat, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 20-200 of human IFNL1 (NP_742152.1) .
Clonality
Polyclonal
Applications
WB, IHC-P
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN- stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type- selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.
Molecular Weight
21898 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Interferon lambda-1
Subcellular Location
Secreted.
Protein Name
Interferon lambda-1

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