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Anti-DNA pol lambda Antibody

CAT: 0519-A00959Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0519-A00959Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Boster Bio Anti-DNA pol lambda Antibody catalog # A00959. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human, Mouse, Rat.
Synonyms
DNA polymerase lambda ; Pol Lambda ;2.7.7.7
Gene Name
POLL
UniProt
Q9UGP5
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human DNA Polymerase lambda. AA range:451-500
Clonality
Polyclonal
Tissue Specificity
Expressed in a number of tissues. Abundant in testis.
Applications
WB, IHC, IF, ELISA
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/mL
Form
Liquid
Function
DNA polymerase that functions in several pathways of DNA repair (PubMed:11457865, PubMed:19806195, PubMed:20693240) . Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA (PubMed:11457865, PubMed:19806195) . Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination (PubMed:19806195, PubMed:20693240) . Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities (PubMed:10982892, PubMed:10887191, PubMed:12809503, PubMed:14627824, PubMed:15537631, PubMed:19806195) . Has also a 5'-deoxyribose-5- phosphate lyase (dRP lyase) activity (PubMed:11457865, PubMed:19806195) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
63482 MW
Gene Name Synonym
DNA polymerase lambda
Subcellular Location
Nucleus
Protein Name
DNA polymerase lambda
Isotype
IgG
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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