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Anti-Intersectin-2 ITSN2 Antibody

CAT: 0519-A06161Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0519-A06161Size:100 µL
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Description
Boster Bio Anti-Intersectin-2 ITSN2 Antibody catalog # A06161. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.
Synonyms
Intersectin-2; SH3 domain-containing protein 1B; SH3P18; SH3P18-like WASP-associated protein; ITSN2; KIAA1256, SH3D1B, SWAP;
Gene Name
ITSN2
UniProt
Q9NZM3
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human ITSN2 (NP_006268.2) .
Clonality
Polyclonal
Tissue Specificity
Expressed in melanocytes (PubMed:23999003) . Ubiquitous. Isoform 1 is primarily expressed in adult heart and liver.
Applications
WB, ICC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Adapter protein that may provide indirect link between the endocytic membrane traffic and the actin assembly machinery. May regulate the formation of clathrin-coated vesicles (CCPs) . Seems to be involved in CCPs maturation including invagination or budding. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR) . Plays a role in dendrite formation by melanocytes (PubMed:23999003) .
Molecular Weight
193461 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Intersectin-2
Subcellular Location
Cytoplasm.
Protein Name
Intersectin-2

UniProtKB · Q9NZM3

Intersectin-2

ITSN2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9NZM3
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ITSN2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Ligand

CalciumMetal-binding

Domain

Coiled coilRepeatSH3 domain

Cellular component

Cytoplasm

Biological process

DifferentiationEndocytosisHost-virus interaction

PTM

Phosphoprotein

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