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Anti-GRPR Antibody

CAT: 0519-A04977Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0519-A04977Size:100 µL
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Description
Boster Bio Anti-GRPR Antibody catalog # A04977. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Synonyms
Gastrin-releasing peptide receptor; GRP-R; GRP-preferring bombesin receptor; GRPR;
Gene Name
GRPR
UniProt
P30550
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human GRPR (NP_005305.1) .
Clonality
Polyclonal
Tissue Specificity
Highly expressed in pancreas. Also expressed in stomach, adrenal cortex and brain.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:2000
Form
Liquid
Function
Receptor for gastrin-releasing peptide (GRP) (PubMed:1655761) . Signals via association with G proteins that activate a phosphatidylinositol-calcium second messenger system, resulting in Akt phosphorylation. Contributes to the regulation of food intake. Contributes to the perception of prurient stimuli and transmission of itch signals in the spinal cord that promote scratching behavior, but does not play a role in the perception of pain. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory (By similarity) .
Molecular Weight
43199 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Gastrin-releasing peptide receptor
Subcellular Location
Cell membrane
Protein Name
Gastrin-releasing peptide receptor

UniProtKB · P30550

Gastrin-releasing peptide receptor

GRPR_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P30550
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
GRPR
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
GRP-R
EC number
—
Processing
—
Secondary accessions
B2R910
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Cellular component

Cell membraneMembrane

PTM

Disulfide bondGlycoproteinLipoproteinPalmitatePhosphoprotein

Molecular function

G protein-coupled receptorReceptorTransducer

Domain

TransmembraneTransmembrane helix

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