Anti-eIF2 Alpha (phospho-S51) EIF2S1 Antibody

• Description:

  Boster Bio Anti-eIF2 Alpha (phospho-S51) EIF2S1 Antibody catalog # A04387S51. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

• Synonyms:

  Eukaryotic translation initiation factor 2 subunit 1; Eukaryotic translation initiation factor 2 subunit alpha; eIF-2-alpha; eIF-2A; eIF-2alpha; EIF2S1; EIF2A;

• Gene Name:

  EIF2S1

• UniProt:

  P05198

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthetic phosphopeptide derived from human eIF2α around the phosphorylation site of Serine 51.

• Clonality:

  Polyclonal

• Applications:

  WB, IHC

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Form:

  Liquid

• Function:

  Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S pre-initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2- GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.

• Molecular Weight:

  36112 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Other Gene Names:

  Eukaryotic translation initiation factor 2 subunit 1

• Subcellular Location:

  Cytoplasm, Stress granule

• Protein Name:

  Eukaryotic translation initiation factor 2 subunit 1