Anti-Transcription factor E3 TFE3 Antibody

• Description:

  Boster Bio Anti-Transcription factor E3 TFE3 Antibody catalog # A01791. Tested in WB, IHC, ICC applications. This antibody reacts with Human, Mouse, Rat.

• Synonyms:

  Transcription factor E3; Class E basic helix-loop-helix protein 33; bHLHe33; TFE3; BHLHE33;

• Gene Name:

  TFE3

• UniProt:

  P19532

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthetic peptide, corresponding to amino acids 133-178 of Human TFE3.

• Clonality:

  Polyclonal

• Tissue Specificity:

  Ubiquitous in fetal and adult tissues.

• Applications:

  WB, IHC, ICC

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Form:

  Liquid

• Function:

  Transcription factor that specifically recognizes and binds E-box sequences (5'-CANNTG-3') . Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T- cell-dependent antibody responses in activated CD4 (+) T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site.

• Molecular Weight:

  61521 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Other Gene Names:

  Transcription factor E3

• Subcellular Location:

  Nucleus.

• Protein Name:

  Transcription factor E3