Anti-Cystathionine beta-synthase CBS Antibody

• Description:

  Boster Bio Anti-Cystathionine beta-synthase CBS Antibody catalog # A00130. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

• Synonyms:

  Cystathionine beta-synthase ;4.2.1.22

• Gene Name:

  CBS

• UniProt:

  P35520

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human CBS (NP_000062.1) .

• Clonality:

  Polyclonal

• Tissue Specificity:

  In the adult strongly expressed in liver and pancreas, some expression in heart and brain, weak expression in lung and kidney. In the fetus, expressed in brain, liver and kidney.

• Applications:

  WB, ICC, IF

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Form:

  Liquid

• Function:

  Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L-homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine. This catabolic route allows the elimination of L-methionine and the toxic metabolite L- homocysteine (PubMed:23981774, PubMed:20506325, PubMed:23974653) . Also involved in the production of hydrogen sulfide, a gasotransmitter with signaling and cytoprotective effects on neurons (By similarity) .

• Molecular Weight:

  60587 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Other Gene Names:

  Cystathionine beta-synthase

• Subcellular Location:

  Cytoplasm

• Protein Name:

  Cystathionine beta-synthase