Anti-Tau (Phospho-S396) MAPT Antibody

• Description:

  Boster Bio Anti-Tau (Phospho-S396) MAPT Antibody catalog # A00097S396-1. Tested in WB, ICC/IF, IHC applications. This antibody reacts with Human, Mouse, Rat.

• Synonyms:

  Microtubule-associated protein tau; Neurofibrillary tangle protein; Paired helical filament-tau; PHF-tau; MAPT; MAPTL, MTBT1, TAU;

• Gene Name:

  MAPT

• UniProt:

  P10636

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthetic phospho-peptide corresponding to residues surrounding Ser396 of human Tau.

• Clonality:

  Polyclonal

• Tissue Specificity:

  Expressed in neurons. Isoform PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system.

• Applications:

  WB, ICC, IF, IHC

• Purification:

  ProA affinity purified

• Form:

  Liquid

• Function:

  Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N- terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

• Molecular Weight:

  78928 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Other Gene Names:

  Microtubule-associated protein tau

• Subcellular Location:

  Cytoplasm, cytosol

• Protein Name:

  Microtubule-associated protein tau