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Methyl ganoderate A acetonide

CAT: 0804-HY-N11641Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N11641Size:1 Each
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Description
Methyl ganoderate A acetonide, a lanostane triterpene, is a natural product that could be isolated from the fruiting bodies of Ganoderma lucidum. Methyl ganoderate A acetonide is a potent AChE inhibitor with an IC50 value of 18.35 μM. Methyl ganoderate A acetonide can be used in research of Alzheimer’s disease (AD) [1].
CAS Number
1346453-53-9
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Natural Products
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/methyl-ganoderate-a-acetonide.html
Solubility
10 mM in DMSO
Smiles
C[C@@]12C3=C4[C@@]5([C@@](C(C)(C(CC5)=O)C)([H])C[C@]3([H])OC(C)(O[C@@]1([H])C[C@]([C@]2(CC4=O)C)([H])[C@H](C)CC(C[C@@H](C)C(OC)=O)=O)C)C
Molecular Formula
C34H50O7
Molecular Weight
570.76
References & Citations
[1]Lee I, et, al. Selective cholinesterase inhibition by lanostane triterpenes from fruiting bodies of Ganoderma lucidum. Bioorg Med Chem Lett. 2011 Nov 1;21 (21) :6603-7.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
AChE

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