Mouse Carboxypeptidase B1 Primacu™ ELISA Kit

Mouse Carboxypeptidase B1 Primacu™ ELISA Kit

• Background: Carboxypeptidase B1, also well known as pancreatic procarboxypeptidase B (PCPB), is a highly pancreas -specific protein (PASP), and has been identified previously as a serum marker for acute pancreatitis and pancreatic graft rejection. As the prototype for those human exopeptidases that cleave off basic C-terminal residues, CPB1 specifically cleaves the C-terminal Arg and Lys residues with a preference for Arg. The B1 and B2 forms of procarboxypeptidase B differ from each other mainly in isoelectric point.The deduced amino acid sequence of PCPB predicts a 416-amino acid preproenzyme consisting of a 15-aa signal peptide, a 95-aa activation peptide and a 37-aa mature chain. The secreted PCPB zymogen is converted to enzymatically active CPB1 by limited proteolysis by trypsin.
• Description: Carboxypeptidase B1
• Origin Species: Mouse
• Reactivity: Mouse
• Target: Carboxypeptidase B1
• Field of Research: Metabolism,Signal transduction
• Assay Type: Sandwich
• Assay Performance Time: 3.5 Hours
• Standard: 8 ng/mL
• Sample Type: Serum, plasma, cell culture supernates
• Detection Range: 12.5-800 pg/mL
• Sensitivity: 2.51 pg/mL
• Storage Temperature: 2-8°C