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Rat Complement Component C1Q Receptor, Cd93 Primacu™ ELISA Kit

CAT:
772-BPE357-02
Size:
5x 96 Well
Price:
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For price, please contact [email protected]
  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
Rat Complement Component C1Q Receptor, Cd93 Primacu™ ELISA Kit - image 1

Rat Complement Component C1Q Receptor, Cd93 Primacu™ ELISA Kit

  • Background: CD93 or C1q receptor 1 (C1qR) is an about 120 kDa O-sialoglycoprotein that within the hematopoietic system is selectively expressed on cells of the myeloid lineage. CD93/C1qR is a highly glycosylated transmembrane protein expressed on monocytes, neutrophils, endothelial cells, and stem cells. CD93 was originally identified as a myeloid cell-surface marker and subsequently associated with an ability to modulate phagocytosis of suboptimally opsonized immunoglobulin G and complement particles in vitro. CD93/C1qR, a receptor expressed during early B-cell development, is reinduced during plasma-cell differentiation. High CD93/CD138 expression was restricted to antibody-secreting cells both in T-dependent and T-independent responses as naive, memory, and germinal-center B cells remained CD93-negative. CD93 was expressed on (pre)plasmablasts/plasma cells, including long-lived plasma cells that showed decreased cell cycle activity, high levels of isotype-switched Ig secretion, and modification of the transcriptional network. CD93 is important for the maintenance of plasma cells in bone marrow niches.
  • Description: Complement component C1q receptor
  • Synonyms: C1qr1;C1qrp
  • Gene Name: Cd93
  • Gene ID: 84398
  • UniProt: Q9ET61
  • Origin Species: Rat
  • Reactivity: Rat
  • Target: CD93
  • Field of Research: Cardiovascular,Immunology,Stem cells
  • Assay Type: Sandwich
  • Assay Performance Time: 3.5 Hours
  • Standard: 10 ng/mL
  • Sample Type: Serum, plasma, cell culture supernates
  • Detection Range: 15.625-1000 pg/mL
  • Sensitivity: 3.66 pg/mL
  • Weight: 68782
  • Storage Temperature: 2-8°C