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Human Complement Component C7, C7 Primacu™ ELISA Kit

CAT: 0772-BPE275-01Size: 96 TestsDry Ice: NoHazardous: No
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CAT#:0772-BPE275-01Size:96 Tests
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Background
Complement component 7 is a component of the complement system. It belongs to the complement C6/C7/C8/C9 family. It contains 1 EGF-like domain, 1 LDL-receptor class A domain, 1 MACPF domain, 2 Sushi (CCP/SCR) domains and 2 TSP type-1 domains. Complement component 7 serves as a membrane anchor. It participates in the formation of Membrane Attack Complex (MAC). People with C7 deficiency are prone to bacterial infection. It is a constituent of MAC that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. Defects in C7 are a cause of complement component 7 deficiency (C7D). A rare defect of the complement classical pathway associated with susceptibility to severe recurrent infections, predominantly by Neisseria gonorrhoeae or Neisseria meningitidis.
Gene ID
730
Reactivity
Human
Target
C7
Field of Research
Immunology
Species
Human