Human Complement Component C7, C7 Primacu™ ELISA Kit

• Background:

  Complement component 7 is a component of the complement system. It belongs to the complement C6/C7/C8/C9 family. It contains 1 EGF-like domain, 1 LDL-receptor class A domain, 1 MACPF domain, 2 Sushi (CCP/SCR) domains and 2 TSP type-1 domains. Complement component 7 serves as a membrane anchor. It participates in the formation of Membrane Attack Complex (MAC). People with C7 deficiency are prone to bacterial infection. It is a constituent of MAC that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. Defects in C7 are a cause of complement component 7 deficiency (C7D). A rare defect of the complement classical pathway associated with susceptibility to severe recurrent infections, predominantly by Neisseria gonorrhoeae or Neisseria meningitidis.

• Description:

  Complement component C7

• Gene Name:

  C7

• Gene ID:

  730

• UniProt:

  P10643

• Origin Species:

  Human

• Reactivity:

  Human

• Target:

  C7

• Field of Research:

  Immunology

• Assay Type:

  Sandwich

• Assay Performance Time:

  3.5 Hours

• Standard:

  20 ng/mL

• Sample Type:

  Serum, plasma, cell culture supernates

• Detection Range:

  23.44-4000 pg/mL

• Sensitivity:

  6.06 pg/mL

• Weight:

  93518

• Storage Temperature:

  2-8°C