Hispidulin

CAT: 0804-HY-N1950-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-N1950-01Size:1 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Hispidulin is a natural flavone with a broad spectrum of biological activities. Hispidulin is a Pim-1 inhibitor with an IC50 of 2.71 μM.
CAS Number
[1447-88-7]
Product Name Alternative
Dinatin
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Pim
Type
Natural Products
Related Pathways
JAK/STAT Signaling
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Hispidulin.html
Purity
99.74
Solubility
DMSO : 62.5 mg/mL (ultrasonic)
Smiles
O=C1C=C(C2=CC=C(O)C=C2)OC3=CC(O)=C(OC)C(O)=C13
Molecular Formula
C16H12O6
Molecular Weight
300.26
Precautions
H302, H315, H319, H335
References & Citations
[1]Chao SW, et al. Total Synthesis of Hispidulin and the Structural Basis for Its Inhibition of Proto-oncogene KinasePim-1. J Nat Prod. 2015 Aug 28;78 (8) :1969-76.|[2]Gao H, et al. Hispidulin induces apoptosis through mitochondrial dysfunction and inhibition of P13k/Akt signalling pathway in HepG2 cancer cells. Cell Biochem Biophys. 2014 May;69 (1) :27-34.|[3]Zhou R, et al. Hispidulin exerts anti-osteoporotic activity in ovariectomized mice via activating AMPK signaling pathway. Cell Biochem Biophys. 2014 Jun;69 (2) :311-7.|[4]Lin TY, et al. Protective effect of hispidulin on kainic acid-induced seizures and neurotoxicity in rats. Eur J Pharmacol. 2015 May 15;755:6-15.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

Related Products

CatalogName
HY-P4327Hispidalin
HY-133223Hispidanin B
HY-100618-01Hispidin
HY-100618R-01Hispidin (Standard)

Alternative Products

CatalogName
MBS3846503-01Hispidulin
A13945-25Hispidulin 25mg
A13945-50Hispidulin 50mg
A13945-5Hispidulin 5mg
A13945-10Hispidulin 10mg
A13945-100Hispidulin 100mg

Popular Products